Therapy for Chronic Viral Hepatitis
نویسنده
چکیده
INTRODUCTION Chronic hepatitis is a liver disease in the form of continuous inflammation and necrosis for at least 6 months. There are many causes of chronic hepatitis, including genetic disorders, drugs, toxins, autoimmune, idiopathic; but the most common cause is viral. The virus that causes chronic viral hepatitis is the hepatitis B virus (HBV), hepatitis C virus (HCV), as well as hepatitis D virus (HDV) together with hepatitis B. Chronic viral hepatitis is the most common cause of chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma in the world, and is currently the main reason for liver transplantation in adults. There is not yet an ideal therapy for chronic viral hepatitis since there is still no specific medication that can produce satisfactory results. Management of chronic viral hepatitis is focused on HBV, HCV, and HDV, since these viruses most commonly cause chronic viral hepatitis. The use of interferon separately or in combination with ribavirin currently predominates therapy for chronic hepatitis due to hepatitis B, C and D virus, besides the use of Lamivudin for the therapy of chronic hepatitis due to hepatitis B virus. Several other anti-virus medications have been tested, but results so far have been unsatisfactory, for reasons discussed below. Therapy for Chronic Viral Hepatitis
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